
ELAVIL-Z
Formulation: Amitriptyline 12.5 mg + Chlordiazepoxide 5mg Tablets
Use For: ELAVIL-Z contains Amitriptyline 12.5 mg and Chlordiazepoxide 5 mg, a combination medication used for the treatment of depression with associated anxiety, psychosomatic disorders, and certain types of chronic pain where emotional distress is a contributing factor.Amitriptyline is a tricyclic antidepressant (TCA) that increases the levels of serotonin and norepinephrine in the brain by inhibiting their reuptake, thereby improving mood and relieving pain. Chlordiazepoxide is a benzodiazepine that enhances the effect of gamma-aminobutyric acid (GABA), producing anxiolytic, sedative, and muscle-relaxant effects.
The combination provides mood stabilization, anxiety reduction, improved sleep, and pain relief. This synergistic effect helps patients with mixed emotional and physical symptoms. Side effects may include drowsiness, dry mouth, constipation, dizziness, and fatigue. Long-term use of Chlordiazepoxide can lead to dependence or tolerance, so this medication should be used under careful medical supervision and is generally intended for short- to medium-term therapy.
ELAVIL-Z Tablets (Amitriptyline 12.5 mg + Chlordiazepoxide 5 mg)
Product Overview:
ELAVIL-Z combines Amitriptyline 12.5 mg and Chlordiazepoxide 5 mg to offer an effective solution for managing anxiety and depression. Amitriptyline, a tricyclic antidepressant, works by increasing serotonin and norepinephrine in the brain, helping to alleviate symptoms of depression. Chlordiazepoxide, a benzodiazepine, provides anxiolytic and sedative effects, reducing feelings of anxiety and agitation. Together, they offer a balanced approach to treating anxiety-related depression and improving mental health.
Therapeutic Uses:
Anxiety disorders
Depression associated with anxiety
Panic attacks
Generalized Anxiety Disorder (GAD)
Sleep disturbances due to anxiety
Psychiatric disorders requiring dual action medication
Mechanism of Action:
Amitriptyline increases the levels of serotonin and norepinephrine in the brain, which helps to improve mood and emotional stability.
Chlordiazepoxide works by calming the central nervous system, providing relief from anxiety and helping patients relax. This combination is particularly beneficial for individuals suffering from both depression and anxiety simultaneously.
Advantages:
Dual-action formula for treating both depression and anxiety
Sedative effects for improved sleep quality
Long-lasting effects with lower doses
Effective in managing symptoms of both mental health and physical anxiety
Convenient combination therapy for better patient compliance
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Amitriptyline 12.5 mg
Product Overview:
Amitriptyline 12.5 mg is a tricyclic antidepressant (TCA) that is primarily used to treat major depressive disorder (MDD) and anxiety-related conditions. Amitriptyline works by increasing the levels of serotonin and norepinephrine in the brain, which helps improve mood, emotional stability, and overall mental well-being. It is also effective in treating chronic pain conditions and insomnia related to depression or anxiety.
Therapeutic Uses:
Major Depressive Disorder (MDD)
Generalized Anxiety Disorder (GAD)
Chronic Pain Management
Post-Traumatic Stress Disorder (PTSD)
Sleep Disorders (related to depression or anxiety)
Panic Disorder
Migraine Prevention
Fibromyalgia Pain Relief
Mechanism of Action:
Amitriptyline works by inhibiting the reuptake of serotonin and norepinephrine in the brain, enhancing their availability. This leads to an improvement in mood, emotional regulation, and reduction of anxiety. It also has sedative properties, which makes it effective for treating insomnia associated with depression and anxiety.
Advantages:
Dual-action antidepressant and anxiolytic properties
Sedative effect helps in improving sleep patterns
Relieves symptoms of both anxiety and depression
Effective for chronic pain management
Cost-effective solution for treating mood disorders
Well-tolerated by most patients when prescribed at appropriate doses
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Chlordiazepoxide 5 mg Tablets
Product Overview:
Chlordiazepoxide 5 mg is a benzodiazepine used primarily for the treatment of anxiety disorders, alcohol withdrawal symptoms, and muscle spasms. It has calming effects on the brain and central nervous system by enhancing the action of a neurotransmitter called gamma-aminobutyric acid (GABA). This helps reduce anxiety, stress, and agitation while providing relief from withdrawal symptoms. Chlordiazepoxide is commonly prescribed to individuals who experience excessive nervousness or agitation and is also used in managing acute alcohol withdrawal.
Therapeutic Uses:
Generalized Anxiety Disorder (GAD)
Panic attacks
Alcohol withdrawal
Muscle spasms
Sedation before surgical procedures
Short-term management of anxiety
Mechanism of Action:
Chlordiazepoxide works by binding to specific receptors in the brain that enhance the activity of GABA, an inhibitory neurotransmitter. This calms the brain's activity, reducing anxiety, tension, and physical symptoms like muscle spasms. It also acts as a mild sedative, helping to induce relaxation and promote sleep in some cases.
Advantages:
Effective for short-term treatment of anxiety and panic disorders
Helps manage alcohol withdrawal symptoms
Quick relief from anxiety-induced physical symptoms (e.g., muscle spasms)
Low dose (5 mg) provides balanced effects with minimal sedation
Well-tolerated with fewer side effects in the prescribed dosage
Short half-life, meaning lower risk of dependence when used appropriately
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