ELAVIL-Z PLUS

Formulation: Amitriptyline HCI. 25 mg. + Chlordiazepoxide 10 mg

Use For: ELAVIL-Z PLUS is a combination medication containing Amitriptyline Hydrochloride 25 mg and Chlordiazepoxide 10 mg, used for the treatment of depression associated with anxiety, somatic symptom disorders, and certain types of chronic pain conditions.
| Amitriptyline, a tricyclic antidepressant (TCA), helps improve mood, relieve nerve-related pain, and enhance sleep by increasing serotonin and norepinephrine levels.
| Chlordiazepoxide, a benzodiazepine, provides anxiolytic (anti-anxiety) and sedative effects, helping to reduce tension, restlessness, and insomnia.

This combination is especially useful in patients suffering from depressive disorders with co-existing anxiety or stress-related symptoms, such as irritable bowel syndrome (IBS), fibromyalgia, or psychosomatic complaints. Common side effects may include drowsiness, dry mouth, constipation, and dizziness. Due to the presence of a benzodiazepine, long-term use should be carefully monitored to avoid dependence or withdrawal symptoms.

✅ ELAVIL-Z PLUS

🔹 Product Overview:

ELAVIL-Z PLUS combines two active ingredients: Amitriptyline HCl 25 mg and Chlordiazepoxide 10 mg. This combination offers a dual-action approach to treating anxiety and depressive disorders. Amitriptyline is a tricyclic antidepressant (TCA) that works by increasing the levels of serotonin and norepinephrine in the brain, improving mood and relieving depressive symptoms. On the other hand, Chlordiazepoxide is a benzodiazepine that calms the brain and central nervous system, effectively reducing anxiety, agitation, and stress.

This combination is ideal for individuals suffering from anxiety and depression where both emotional stability and anxiety relief are needed simultaneously. It also provides therapeutic benefits for patients with insomnia, muscle spasms, and panic disorders.

🔹 Therapeutic Uses:

Major Depressive Disorder (MDD)
Generalized Anxiety Disorder (GAD)
Insomnia related to anxiety or depression
Acute Anxiety and Panic Attacks
Chronic stress and emotional well-being
Muscle spasms and tension
Post-traumatic Stress Disorder (PTSD)

🔹 Mechanism of Action:

Amitriptyline works by inhibiting the reuptake of serotonin and norepinephrine, improving mood, reducing anxiety, and enhancing emotional stability.
Chlordiazepoxide binds to GABA receptors in the brain, inducing a calming effect, reducing anxiety, muscle spasms, and promoting relaxation.
Together, these medications provide comprehensive relief for patients suffering from both anxiety and depression, while also addressing physical symptoms of tension and agitation.

🔹 Advantages:

Dual-action treatment for anxiety and depression
Provides immediate relief from acute anxiety symptoms
Reduces both mental and physical tension
Improves sleep quality for patients with insomnia due to anxiety
Well-suited for short-term use for anxiety and depression
Effective for chronic stress management
Fast acting, with noticeable effects within a short time

🔹 For PCD Pharma Franchise:

Exclusive marketing rights
Promotional support (MR bags, samples, visual aids)
Competitive pricing and premium quality production
Fast delivery and full regulatory support
Monopoly rights in your region
Branding and distribution support
Customizable packaging for branding

🔹 For Third-Party Manufacturing:

Manufactured in WHO-GMP certified facilities
Bulk production under your brand name
Custom packaging and labeling options
International-standard quality and documentation
Regulatory compliance for global markets
On-time delivery with full support and documentation

✅ Amitriptyline HCl 25 mg

🔹 Product Overview:

Amitriptyline HCl 25 mg is a tricyclic antidepressant (TCA) used primarily to treat major depressive disorder (MDD), anxiety, chronic pain, and insomnia. It works by increasing the levels of serotonin and norepinephrine in the brain, which helps improve mood and alleviate symptoms of depression. Amitriptyline is also effective for managing neuropathic pain and is commonly prescribed for chronic headaches, migraine prevention, and fibromyalgia.

🔹 Therapeutic Uses:

Major Depressive Disorder (MDD)
Generalized Anxiety Disorder (GAD)
Chronic pain management (e.g., neuropathic pain, fibromyalgia)
Migraine prevention
Insomnia and sleep disturbances
Post-traumatic Stress Disorder (PTSD)
Obsessive-Compulsive Disorder (OCD)
Chronic tension headaches

🔹 Mechanism of Action:

Amitriptyline works by inhibiting the reuptake of serotonin and norepinephrine in the brain, increasing their levels and improving mood. It also has a sedative effect, which helps those with sleep disturbances related to depression or anxiety. The drug can also block certain receptors in the nervous system, which helps with pain management, especially in neuropathic conditions.

🔹 Advantages:

Dual benefit for both mood stabilization and pain management
Effective for anxiety and depression relief
Improves sleep quality in patients with insomnia
Well-tolerated at 25 mg dosage
Can be used as an adjunct for migraine prevention
Long-acting, offering sustained relief
Safe for short-term and long-term treatment under medical supervision

🔹 For PCD Pharma Franchise:

Exclusive marketing rights
Promotional support (MR bags, samples, visual aids)
High-quality, cost-effective manufacturing
Quick delivery and regulatory assistance
Monopoly marketing rights for regions
Customizable packaging for brand visibility

🔹 For Third-Party Manufacturing:

Manufactured in WHO-GMP certified facilities
Bulk production under your brand name
Custom packaging and labeling options
International-standard quality and documentation
Full regulatory support for global markets
Efficient supply chain management with timely deliveries

✅ Chlordiazepoxide 10 mg

🔹 Product Overview:

Chlordiazepoxide 10 mg is a benzodiazepine medication used primarily for the treatment of anxiety, acute alcohol withdrawal symptoms, and muscle spasms. It works by enhancing the effects of GABA (gamma-aminobutyric acid), a neurotransmitter that inhibits brain activity, producing a calming effect. This makes Chlordiazepoxide effective in reducing anxiety, nervousness, and agitation, as well as helping to manage the symptoms of alcohol withdrawal.
It is commonly prescribed for patients experiencing short-term anxiety, stress, or agitation, and it can also be used for preoperative sedation or in insomnia cases when caused by anxiety.

🔹 Therapeutic Uses:

Anxiety disorders
Acute alcohol withdrawal syndrome
Muscle spasms and spasticity
Preoperative sedation
Nervousness and agitation relief
Insomnia (due to anxiety)
Panic attacks
Short-term stress relief

🔹 Mechanism of Action:

Chlordiazepoxide 10 mg enhances the action of the neurotransmitter GABA, which helps calm the brain and central nervous system. By binding to specific receptors in the brain, it reduces nerve excitability, providing relief from anxiety, muscle spasms, and other conditions that involve excessive central nervous system activity.

🔹 Advantages:

Fast-acting anxiety relief
Effective for short-term treatment of anxiety and agitation
Reduces muscle spasms effectively
Sedative effect to help with sleep disorders
Alcohol withdrawal management
Well-tolerated at 10 mg dose
Safe and effective for short-term use

🔹 For PCD Pharma Franchise:

Exclusive marketing rights
Promotional support (MR bags, samples, visual aids)
Affordable pricing and high-quality production
Quick delivery and regulatory support
Monopoly marketing rights for your region
Customizable packaging for brand visibility

🔹 For Third-Party Manufacturing:

Manufactured in WHO-GMP certified facilities
Bulk production under your brand name
Custom packaging and labeling options
International-standard quality and documentation
Regulatory compliance for global markets
Efficient delivery and full support

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