LIFI TAB
Formulation: Chlordiazepoxide 5 + Clidinum Bromide 2.5 mg
Use For: LIFI TAB contains a combination of Chlordiazepoxide 5 mg and Clidinium Bromide 2.5 mg, primarily used for the management of gastrointestinal disorders, especially those involving irritable bowel syndrome (IBS), peptic ulcers, and gastritis, often with associated anxiety or stress-related symptoms.
Chlordiazepoxide is a benzodiazepine that works by enhancing the effect of GABA (gamma-aminobutyric acid), a neurotransmitter that reduces brain activity. This results in calming effects, helping to reduce anxiety, muscle spasms, and agitation, which can often accompany gastrointestinal issues.
Clidinium Bromide is an anticholinergic (antimuscarinic) agent that works by blocking the action of acetylcholine, a neurotransmitter involved in the contraction of smooth muscles in the gastrointestinal tract. This results in reduced gut motility, providing relief from abdominal cramps, diarrhea, and other gastrointestinal symptoms associated with IBS and similar conditions.
LIFI TAB (Chlordiazepoxide 5 mg + Clidinium Bromide 2.5 mg)
Product Overview:
LIFI TAB combines Chlordiazepoxide 5 mg and Clidinium Bromide 2.5 mg into one tablet to offer an effective solution for managing gastrointestinal issues and anxiety-related disorders. Chlordiazepoxide is a benzodiazepine, widely used for anxiety relief and controlling symptoms of stress, while Clidinium Bromide is an anticholinergic agent that helps reduce spasm and acid secretion in the stomach. Together, they help relieve abdominal discomfort, cramps, and anxiety, making this combination effective for individuals dealing with both gastrointestinal symptoms and stress.
Therapeutic Uses:
Treatment of Irritable Bowel Syndrome (IBS)
Abdominal cramps or discomfort
Gastrointestinal spasm relief
Management of anxiety
Generalized anxiety disorder (GAD)
Gastrointestinal disorders associated with stress
Peptic ulcer disease (as part of an adjunctive therapy)
Mechanism of Action:
Chlordiazepoxide works by enhancing the effect of GABA (Gamma-Aminobutyric Acid) in the brain. GABA is a neurotransmitter that inhibits brain activity, producing calming and anxiolytic effects that help alleviate anxiety and stress.
Clidinium Bromide acts as an anticholinergic, blocking the action of acetylcholine, which in turn helps in relaxing the smooth muscles of the gastrointestinal tract, thus reducing cramps and spasms.
Advantages:
Dual-action formulation providing both anxiolytic (anxiety-reducing) and antispasmodic effects.
Effective for IBS and gastrointestinal disorders with a combination of anxiety relief.
Reduces symptoms of both stress-induced and organic gastrointestinal issues.
Fast-acting with a convenient dosing regimen.
Helps reduce abdominal discomfort, bloating, and cramps associated with stress.
Ideal for patients with gastrointestinal issues and co-existing anxiety disorders.
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Chlordiazepoxide 5 mg
Product Overview:
Chlordiazepoxide 5 mg is a medication belonging to the benzodiazepine class, widely prescribed for the treatment of anxiety disorders and acute anxiety episodes. It helps in managing symptoms associated with stress, panic attacks, and anxiety. Chlordiazepoxide is effective in promoting relaxation by enhancing the effects of the neurotransmitter GABA (Gamma-Aminobutyric Acid) in the brain, which helps reduce excessive neural activity. This medication is often used in combination with other therapies to address generalized anxiety disorder (GAD), alcohol withdrawal symptoms, and other stress-induced disorders.
Therapeutic Uses:
Generalized Anxiety Disorder (GAD)
Acute anxiety attacks
Panic disorder
Alcohol withdrawal management
Pre-surgical anxiety management
Muscle relaxation for tension-related disorders
Short-term treatment of anxiety and stress-related symptoms
Mechanism of Action:
Chlordiazepoxide works by binding to GABA receptors in the brain, enhancing the activity of GABA, which is an inhibitory neurotransmitter. This action decreases the activity of the central nervous system, resulting in a calming effect, relaxation, and reduced anxiety. It also has mild sedative effects, which help manage stress-related symptoms, including insomnia and muscle tension.
Advantages:
Effective for short-term management of anxiety disorders and panic attacks
Helps alleviate stress and its physical symptoms (e.g., muscle tension, agitation)
Mild sedative effects, which can improve sleep without causing excessive drowsiness
Rapid onset of action, providing quick relief from anxiety
Suitable for treating alcohol withdrawal symptoms and related agitation
Well-tolerated in short-term use, with minimal side effects when taken as directed
Can be used in combination with other therapeutic agents for comprehensive anxiety management
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Clidinium Bromide 2.5 mg
Product Overview:
Clidinium Bromide 2.5 mg is an anticholinergic medication commonly used to treat irritable bowel syndrome (IBS) and functional gastrointestinal disorders. It helps alleviate cramping, bloating, and abdominal pain by relaxing the muscles in the intestines and slowing down the action of the digestive system. Clidinium works by blocking the action of acetylcholine, a neurotransmitter that causes muscle contractions in the gastrointestinal tract. By doing so, it helps to ease digestive discomfort and control spasm-related conditions.
Therapeutic Uses:
Irritable Bowel Syndrome (IBS)
Abdominal cramps and pain associated with gastrointestinal disorders
Intestinal spasms
Bloating and discomfort due to digestive issues
Peptic ulcer disease, in combination with other medications for acid control
Diarrhea-predominant IBS for symptom control
Mechanism of Action:
Clidinium Bromide works by inhibiting the action of acetylcholine at the muscarinic receptors in the gastrointestinal tract. Acetylcholine is responsible for muscle contractions in the intestines. By blocking this action, Clidinium helps relax the muscles, reduce spasms, and control excessive secretions, thus alleviating symptoms of IBS and other digestive conditions.
Advantages:
Effective for managing IBS-related abdominal discomfort
Helps reduce bloating and cramping, improving overall digestive health
Provides relief from gastrointestinal spasms, helping to control symptoms of functional gastrointestinal disorders
Well-tolerated for short-term use in relieving digestive discomfort
Improves quality of life for patients suffering from IBS and similar conditions
Can be used in combination with other medications for enhanced therapeutic effect
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